Available Dosage Strengths
200 mg/mL
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Testosterone Cypionate 80% / Propionate 20% Injection Description1-6
Testosterone Cypionate 80%_Propionate 20% Injection is a compounded injectable testosterone ester blend consisting of 80% testosterone cypionate and 20% testosterone propionate. Both esters have been used in testosterone replacement therapy (TRT) to treat male hypogonadism. The two testosterone esters included in the compound have different pharmacokinetic profiles that provide a stable and sustained release of testosterone, potentially reducing the frequency of injections and minimizing fluctuations in hormone levels. Testosterone propionate has a half-life (4.5 days) while testosterone cypionate has a longer half-life (8 days).3,4 Testosterone that has not been esterified has a half-life of as short as 10 minutes. Thus, the esterification process may allow for a longer duration of effect.
Mechanism of Action1-6
Testosterone cypionate and testosterone propionate are both esterified forms of testosterone. The esterification occurs on the 17b carbon of the testosterone structure. The esters extend the duration of action and are useful for less frequent, intramuscular, or subcutaneous injections. Once administered, the esters are cleaved, releasing free testosterone into the bloodstream. Testosterone then binds to androgen receptors in various tissues, exerting anabolic and androgenic effects. Testosterone has a role in influencing the development and maintenance of male secondary sexual characteristics, stimulation of muscle and bone growth, and regulation of libido and mood.
Common1
Contraindications1
Precautions1
Store at 20°C to 25°C (68°F to 77°F) in a dry place, away from heat and light. DO NOT REFRIGERATE. Do not freeze. Keep out of reach of children.
This information is for educational purposes only. This compounded product has not been reviewed, approved, or evaluated by the Food and Drug Administration for safety and effectiveness. This product is not intended to diagnose, treat, cure, or prevent any disease. No claims are made regarding treatment, cure, or prevention of any disease or condition.
This information may not cover all possible drug information about this product. Call your doctor for medical advice and/or about side effects. You may report side effects to the FDA at 1-800-FDA-1088. A Wells Pharmacy Network pharmacist will be happy to answer any questions. For consultation, please call 1-800-622-4510.
