Available Dosage Strengths
2.5 mg
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Letrozole Tablets Description1,2
Letrozole, an aromatase inhibitor (nonsteroidal), is used in postmenopausal women for breast cancer and for the treatment of advanced breast cancer.
References
Mechanism of Action1,2
Letrozole binds to heme group of the cytochrome P450 subunit of the aromatase (enzyme) resulting in a reduction of estrogen (estrone, estradiol and estrone sulfate) biosynthesis in all tissues. The drug decreases estrogen levels by preventing the conversion of androgens to estrogen.
Common1
Contraindications1,2
Precautions1,2
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