(Commercial Product)
Available Dosage Strengths
1,000 mcg/mL
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Cyanocobalamin (B12) Injection1
Cyanocobalamin, synthetic compound of vitamin B12, supports several methylation reactions in the body. It is essential for growth, cell reproduction, hematopoiesis, and nucleoprotein and myelin synthesis. Cells characterized by rapid division (epithelial cells, bone marrow, myeloid cells) appear to have the greatest requirement for cyanocobalamin.
Cyanocobalamin has many approved indications (many that lead to a deficiency of cyanocobalamin through an impairment of absorption of cyanocobalamin) including:
Cyanocobalamin can be administered via intramuscular (IM) or subcutaneous (SC) routes.
References
Mechanism of Action1-3
Vitamin B12 is important for division and growth of the cell. It is converted to coenzyme B12 in the body and in this form facilitates the conversion of homocysteine to methionine (methylcobalamin) and plays an important role in converting methylmalonyl-coenzyme A to succinyl-Co-A (fatty acid and amino acid metabolism). Without coenzyme B12, tetrahydrofolate cannot be produced from 5-methyl tetrahydrofolate leading to folate deficiency. In addition, vitamin B12 is needed to produce myelin and is important for axon and nerve development. Gastrointestinal absorption of vitamin B12 depends on the presence of sufficient intrinsic factor and calcium ions.
Common1-3
Contraindications1-3
Precautions1-3
Store at 20°C to 25°C (68°F to 77°F). Do not freeze. Protect from light and moisture. Keep in original packaging and out of reach of children.
This information is for educational purposes only.
Wells Pharmacy Network distributes certain FDA-approved commercial products that are manufactured by third-party pharmaceutical companies. These products are not compounded or manufactured by Wells Pharmacy Network. Product availability at the time of dispensing may vary due to supply chain conditions.
This information is a summary. It may not cover all possible drug information about this product. For complete product information, refer to the manufacturer’s prescribing information and labeling. Call your doctor for medical advice and/or about side effects. You may report side effects to the FDA at 1-800-FDA-1088. A Wells Pharmacy Network pharmacist will be happy to answer any questions. For consultation, please call 1-800-622-4510.
