+Chronium +Carnitine (Trimtropic II) Injection
Available Dosage Strengths
20 mg / 40 mg / 5 mg / 33 mg / 2 mg / 1 mg / 25 mcg / 25 mg/mL
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MI / B-Complex + Chromium + Carnitine (Trimtropic II) Injectable Description1-10
Trimtropic II is a combination of the ingredients below, formulated to support weight loss along with proper nutrition, diet and exercise programs.
Methionine- Essential sulfur-containing amino acid used in protein synthesis and methylation pathways.
Inositol- A sugar alcohol structurally similar to glucose; involved in cell signaling and insulin response.
Riboflavin (B₂)- Water-soluble vitamin essential for oxidative energy metabolism and enzyme function.
Niacinamide (B₃)- Amide form of niacin; supports cellular energy and redox reactions as part of NAD/NADP coenzymes.
Pantothenic Acid (B5) -Vitamin B₅; required for coenzyme A synthesis and fatty acid metabolism.
Methylcobalamin (B12)- Active form of vitamin B₁₂; essential for methylation/methyl transfer, nerve function, and red blood cell production.
Chromium Picolinate- Trace mineral complex with evidence to support insulin action (potentially reducing insulin resistance) and support glucose metabolism.
L-Carnitine- An amino acid derivative that transports fatty acids into mitochondria for oxidation, with a high concentration in skeletal and cardiac muscle.
Mechanism of Action 1-10
Methionine- Supports methylation reactions and may assist in lipid metabolism; methionine restriction is associated with improved metabolic markers in some models.
Inositol- May improve insulin signaling via phosphatidylinositol pathways; explored in PCOS and metabolic syndrome.
Riboflavin (B₂)- Cofactor in flavoprotein enzymes (FAD, FMN) involved in carbohydrate, fat, and protein metabolism.
Niacinamide (B₃)- Provides NAD/NADP for redox reactions critical to ATP production and lipid metabolism.
Pantothenic Acid- Integral for CoA and acyl-carrier proteins, enabling fatty acid oxidation and biosynthesis.
Methylcobalamin (B12)- Supports homocysteine remethylation and DNA synthesis; assists in energy conversion indirectly.
Chromium Picolinate- May enhance insulin receptor sensitivity and carbohydrate metabolism.
L-Carnitine- Transports long-chain fatty acids across mitochondrial membranes for beta-oxidation (energy production).
Adverse Effects 1-10
Common
Methionine- Possible increase in homocysteine levels; rare GI discomfort or headaches.
Inositol- Generally well tolerated; high doses may cause nausea, bloating, dizziness, or fatigue.
Riboflavin (B₂)- Generally safe; may cause bright yellow urine.
Niacinamide (B₃)- High doses may cause flushing (less so than niacin), nausea, or elevated liver enzymes.
Pantothenic Acid- Mild GI upset or diarrhea at high doses.
Methylcobalamin (B12)- Injection site soreness, rare diarrhea or skin rash.
Chromium Picolinate- Headache, dizziness, nausea; high doses may affect kidney or liver function.
L-Carnitine- Nausea, vomiting, diarrhea; insomnia and restlessness reported with higher doses.
Contraindications and Precautions 1-10
Methionine- Use caution in cardiovascular disease, hyperhomocysteinemia, or hepatic impairment.
Inositol- Monitor use in those with bipolar disorder or insulin therapy; consult physician.
Riboflavin (B₂)- No known major contraindications; generally safe in most populations.
Niacinamide (B₃)- Caution in liver disease or diabetes; monitor liver enzymes.
Pantothenic Acid- Generally safe; rare hypersensitivity reactions have been reported.
Methylcobalamin- Avoid in hereditary optic neuropathy (Leber’s disease); monitor for polycythemia.
Chromium Picolinate- Avoid in patients with renal or hepatic impairment; caution with concurrent NSAIDs or corticosteroids.
L-Carnitine- Avoid or closely monitor in seizure disorders and end-stage renal disease; not
recommended during pregnancy without supervision.
Store at room temperature; protect from light moisture and heat. DO NOT REFRIGERATE.
This sheet is a summary. It may not cover all possible drug information about this product. Call your doctor for medical advice and/or about side effects. You may report side effects to the FDA at 1-800-FDA-1088. A Wells Pharmacy Network pharmacist will be happy to answer any questions. For consultation, please call 1-800-622-4510.
