(Ship Cold)
Available Dosage Strengths
16.6 mg / 2 mg/mL
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Tirzepatide_Niacinamide Description1-4
Tirzepatide_Niacinamide Injection is a combination of tirzepatide and niacinamide. Tirzepatide is a dual incretin receptor agonist, acting on both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, while niacinamide (vitamin B3) contributes to mitochondrial support by assisting with cellular energy conversion, and acts as an antioxidant.
Tirzepatide1-3
Tirzepatide is a once-weekly subcutaneous injection indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It is also FDA approved for chronic weight management under the brand name Zepbound in certain populations. Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist.
Niacinamide(vitamin B3)5-7
Niacinamide (also known as niacin or nicotinic acid) is a vitamin (vitamin B3) that is an essential nutrient. Niacinamide can be found in bran, yeast, eggs, peanuts, poultry, red meat, fish, whole-grain cereals, legumes, and seeds. It plays a key role in helping the body convert food into energy and protecting against oxidative stress by regulating oxidative enzymes and acting directly as an antioxidant. It is used to treat dermatological diseases, central nervous system diseases, and increased cholesterol levels.
Tirzepatide1-4
Tirzepatide exerts its effects through dual incretin receptor agonism, targeting both:
– Enhances insulin secretion
– Reduces glucagon secretion
– Promotes lipid metabolism and may contribute to weight loss
– Delays gastric emptying
– Reduces appetite
– Stimulates insulin release in a glucose-dependent manner
– Inhibits glucagon release during hyperglycemia
Niacinamide 5-7
Niacinamide contributes to supporting mitochondrial function and metabolic pathways through its conversion to NAD⁺/NADP⁺.It is a vital component in the oxidized state of nicotinamide adenine dinucleotide (NAD, or coenzyme 1) and the reduced form of nicotinamide adenine dinucleotide phosphate (NADP, or coenzyme 2). The coenzymes, NAD and NADP) facilitate essential oxidation-reduction reactions. These coenzymes play key roles in glycolysis, pyruvate metabolism, protein and amino acid metabolism, pentose biosynthesis, glycerol metabolism, synthesis of high-energy phosphate bonds, and fatty acid metabolism.
Adverse Reactions1-4
Common
Most adverse reactions are gastrointestinal in nature and dose-dependent:
Contraindications & Precautions1-4
Contraindications:
Precautions:
Store refrigerated at 36°F to 46°F (2°C – 8°C). Discard within 28 days of puncture or according to the beyond-use date. Do not freeze. Keep out of reach of children.
This sheet is a summary. It may not cover all possible drug information about this product. Call your doctor for medical advice and/or about side effects. You may report side effects to the FDA at 1-800-FDA-1088. A Wells Pharmacy Network pharmacist will be happy to answer any questions. For consultation, please call 1-800-622-4510.
