(Ship Cold)
Available Dosage Strengths
16.6 mg / 7.5 mg/mL
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Tirzepatide_Glycine Description 1-4
Tirzepatide_Glycine injection is a combination of tirzepatide and glycine. Tirzepatide is a dual incretin receptor agonist, acting on both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, while glycine is an amino acid that contributes to the building of proteins.
Tirzepatide1-3
Tirzepatide is a novel dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. It is a once-weekly subcutaneous injection indicated as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus and for chronic weight management.
Glycine5-9
Glycine is an amino acid that can be synthesized in the body. It is an amino acid that is found in the structure of proteins in the body including collagen, creatine, and purine nucleotides. In the plasma, it accounts for 11.5% of the total amino acids. It has been studied in marathon runners for its anti-inflammatory and immunomodulatory activity and its ability to benefit physical performance and muscle growth. It also has been shown to have a role in the prevention of lung injuries, gastric ulcers and during hemorrhagic and endotoxic shock.
Tirzepatide1-3
Tirzepatide exerts its effects through dual incretin receptor agonism, targeting both:
– Enhances insulin secretion
– Reduces glucagon secretion
– Promotes lipid metabolism and may contribute to weight loss
– Delays gastric emptying
– Reduces appetite
– Stimulates insulin release in a glucose-dependent manner
– Inhibits glucagon release during hyperglycemia
Glycine5-9
Glycine exerts its anti-inflammatory effects by inhibiting cytokine synthesis, reducing serum transaminase levels and works on decreasing calcium levels inside cells. The cytokines that glycine inhibits are TNF-a, interleukin-6, interleukin-1b. It also increases the levels of anti-inflammatory cytokines including interleukin-10 found in macrophages and leucocytes.
Adverse Reactions 1-4,8
Most adverse reactions are gastrointestinal in nature and dose-dependent:
Contraindications & Precautions 1-4
Contraindications:
Precautions:
Pregnancy & Lactation: - No adequate data; use only if benefit outweighs potential risk. Discontinue at least 1 month prior to a planned pregnancy due to long half-life
Store refrigerated at 36°F to 46°F (2°C – 8°C). Discard within 28 days of puncture or according to the beyond-use date. Do not freeze. Keep out of reach of children.
This sheet is a summary. It may not cover all possible drug information about this product. Call your doctor for medical advice and/or about side effects. You may report side effects to the FDA at 1-800-FDA-1088. A Wells Pharmacy Network pharmacist will be happy to answer any questions. For consultation, please call 1-800-622-4510.
