Lancapsil-N
Available Dosage Strengths
0.5% / 5% / 1.2% / 0.5% / 5% / 0.55% / 10,000 u/gm
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This scar gel combines ingredients that may help reduce the appearance of scars by promoting skin regeneration and soothing inflammation. Together, these ingredients may work to even out skin tone, fade discoloration, and improve the overall texture of the skin.
Lipoic Acid1-3
Lipoic acid, known as alpha lipoic acid, may function as an antioxidant and anti-inflammatory for the skin. It is thought to reduce the effects of skin aging or skin that has gone through damage.
Niacinamide4,5
Niacinamide, a form of vitamin B3, is a water-soluble vitamin that is essential for cellular metabolism. Niacin and niacinamide are both forms of vitamin B3 but have slight structural differences. It has been shown to support the skin barrier, act as an anti-inflammatory, antioxidant and skin-brightening agent. Topically, niacinamide has been shown to be helpful for acne vulgaris, melasma, psoriasis and aging skin.
Caffeine6,7
Caffeine, structurally a xanthine, acts as an adenosine-receptor antagonist. It may have antioxidant, anti-inflammatory properties, and vasodilatory effects on the vasculature to increase blood flow to the wound site. Caffeine may also inhibit skin fibrosis and scar formation.
Pentoxifylline8,9
Pentoxifylline may have anti-inflammatory effects and inhibit fibroblast activity. Because of its activity in inhibiting fibroblast activity, the drug may reduce or prevent scar and keloid formation.
Azelaic Acid10
Azelaic acid may have antibacterial, anti-inflammatory and antioxidant properties. It has been used for dermatological purposes for the following indications: rosacea, acne vulgaris, melasma and to prevent scar formation.
Naltrexone11-13
Naltrexone, an opioid receptor antagonist, may have anti-inflammatory activity and in low doses may benefit dermatological indications.
Vitamin D14-16
Vitamin D, a fat soluble, vitamin, was discovered in the early 1920s. It is available in two main types D2, ergocalciferol, and D3, cholecalciferol. It is an essential vitamin that supports bone health, enhances immune function, and helps to regulate calcium and phosphorous levels. Vitamin D, which is inert in the body, can be obtained from sun exposure, foods and supplements and must be activated in the body to have a physiological effect. It may have immunomodulatory, anti-inflammatory activity, and antioxidant activity for the skin.
Lipoic Acid1-3
Lipoic acid, as an antioxidant for dermatological properties, may act as a free radical scavenger. It also decreases the deposition of collagen in the skin and may lower glycosaminoglycans which are secreted by fibroblasts. In addition, lipoic acid may decrease pro-inflammatory cytokines and transforming growth factor β1. This activity may work to decrease or minimize scar formation on the skin.
Niacinamide4,5
Niacinamide may inhibit melanosome transfer, increase ceramide synthesis and act as an anti-inflammatory. Specifically, niacinamide is thought to inhibit proteins (sirtuins and poly-(ADP-ribose) polymerases) in the skin and reduce reactive oxygen species to decrease inflammation. Niacinamide may decrease underlying inflammation to decrease hyperpigmentation and hypertrophic changes in a scar.
Caffeine6,7
Caffeine may reduce collagen synthesis and overall fibroblast activity. It also decreases the activity of keratinocytes and interferes with transforming growth factor beta activation.
Pentoxifylline8,9
Pentoxifylline may decrease collagen, fibronectin, and glycosaminoglycan production leading to decreased fibroblast activity in the skin.
Azelaic Acid10
Azelaic acid may decreases the transcription of cytokines and chemokines to decrease blood flow and inflammation in a scar. It also may prevent the generation of reactive oxygen species and decrease oxidative damage.
Naltrexone11-13
Naltrexone may have immunomodulatory activity by decreasing Toll-like receptors signaling, minimizing release of proinflammatory cytokines (tumor necrosis factor, interleukin-6, interleukin- 12), inhibiting T lymphocyte proliferation, and down-regulating the expression of chemokine receptors in the skin. These activities may decrease inflammation and prevent scar formation.
Vitamin D14-16
Vitamin D decreases inflammation in the skin through the inhibition of the production of collagen by inhibiting the formation of fibroblast cells and development of fibrous tissue. It decreases the production of extracellular matrix triggered by TGF-β to facilitate anti-inflammatory activity.
Common1
Contraindications1,2
Precautions1,2
Store at 20°C to 25°C (68°F to 77°F). Protect from light, moisture, and heat.
This information is for educational purposes only. This compounded product has not been reviewed, approved, or evaluated by the Food and Drug Administration for safety and effectiveness. This product is not intended to diagnose, treat, cure, or prevent any disease. No claims are made regarding treatment, cure, or prevention of any disease or condition.
This information may not cover all possible drug information about this product. Call your doctor for medical advice and/or about side effects. You may report side effects to the FDA at 1-800-FDA-1088. A Wells Pharmacy Network pharmacist will be happy to answer any questions. For consultation, please call 1-800-622-4510.
