(FA/C/E Complex)
Available Dosage Strengths
15% / 0.5% / 1%
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FA/C/E Complex formula contains ascorbic acid, ferulic acid and vitamin E. These compounds may work together to brighten the skin, reduce the appearance of fine lines and protect against environmental stressors. This powerful antioxidant combination may help improve skin tone and texture while providing essential hydration and protection. It may also help to decrease skin aging including fine lines, dullness, dryness, and loss of elasticity.
Ascorbic Acid1-5
Ascorbic acid (vitamin C) an antioxidant and a water-soluble vitamin is a critical co-factor for collagen biosynthesis, carnitine and catecholamine metabolism, and systemically dietary iron absorption. Ascorbic acid is an important component to ensure that skin has a healthy integrity. Along with its antioxidant properties for the skin, it may have the following activities: as an anti-inflammatory, as a depigmenting agent, and it may help in the development of collagen. Ascorbic acid deficiency causes skin aging. Thus, the external supplementation of ascorbic acid may be one of the attractive strategies for skin antiaging.
Ascorbic acid is not made in the body and needs to be obtained through diet or through supplements. Dietary sources of ascorbic acid include citrus fruits, berries, tomatoes, potatoes and green leafy vegetables.
Ferulic Acid6,7,8
Ferulic Acid, a phenolic compound, is found in the cell walls of leaves and roots of many fruits and vegetables. It has potential medicinal properties including antioxidant, ant-inflammatory, anti-aging and antimicrobial activity. Although the chemical has poor solubility potentially limiting its use for therapeutic purposes, advances in nanotechnology have improved ferulic acid’s pharmacokinetic profile by encapsulating it in a matrix that is compatible with physiological fluids.
Vitamin E9
Vitamin E (or tocopherol), a fat-soluble vitamin, that functions as an antioxidant, protecting the cell membrane. The body does not form vitamin E and needs to be provided it exogenously. Vitamin E may prevent reactive oxygen species from forming and protect the biosynthesis of collagen and glycosaminoglycans in skin. Vitamin E may benefit the following dermatological conditions: atopic dermatitis, epidermolysis bullosa, psoriasis, wound healing, melasma, scleroderma, acne vulgaris and melasma.
Ascorbic Acid1-5
Ascorbic acid functions in the aqueous compartments of the cell. As an antioxidant, ascorbic acid neutralizes free radicals by donating electrons to prevent oxidative stress. Reactive oxygen species are formed when skin is exposed to ultraviolet light forming superoxide ions, peroxide and singlet oxygen species. Ascorbic acid facilitates collagen development. It plays an important role in the maturation of collagen. It is a critical co-factor for prolyl hydroxylase and lysl hydroxylase. The level of ascorbic acid in the skin is directly tied to the structural integrity of dermal collagen. As a depigmenting agent, ascorbic acid interacts with copper ions at the tyrosinaseactive site and inhibits action of the enzyme tyrosinase, thereby minimizing the melanin formation. Ascorbic acid interferes with NFkB activity and thus decreases the activity of a number of proinflammatory cytokines such as TNFalfa, IL1, IL6 and IL8.
Ferulic Acid6,7,8
Ferulic Acid may have several methods to support its role as a topical formulation including the following:
It may also modulate tyrosine kinase activity and have antimicrobial activity by disrupting bacterial cell membrane.
Vitamin E9
Gamma (γ) tocopherol is the most abundant vitamin E in the diet and alpha (α) tocopherol is the most abundant form of vitamin E in the skin. These forms of vitamin E are thought to inhibit the production of prostaglandin and nitric oxide, protect skin cells from sunburn and generally prevent oxidative stress in the skin.
Common 1-9
Contraindications: 1-9
Precautions: 1-9
Store at 20°C to 25°C (68°F to 77°F) in a dry place, away from heat and light. Keep out of reach of children.
This information is for educational purposes only. This compounded product has not been reviewed, approved, or evaluated by the Food and Drug Administration for safety and effectiveness. This product is not intended to diagnose, treat, cure, or prevent any disease. No claims are made regarding treatment, cure, or prevention of any disease or condition.
This information may not cover all possible drug information about this product. Call your doctor for medical advice and/or about side effects. You may report side effects to the FDA at 1-800-FDA-1088. A Wells Pharmacy Network pharmacist will be happy to answer any questions. For consultation, please call 1-800-622-4510.
