Latanoprost (LatanoSTIM) Hair Serum

Available Dosage Strengths

0.06%

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Product Overview

Description

Latanoprost is a prostaglandin F2α (PGF2α) analog primarily indicated for the treatment of open-angle glaucoma and ocular hypertension. There is evidence that the drug promotes hair growth, particularly in androgenetic alopecia (AGA) and eyelash/eyebrow hypotrichosis^1-3 Its role in hair regrowth was first noted due to its adverse effect of increased eyelash growth in glaucoma patients.^1-5

Mechanisms of Action

Latanoprost binds to the prostaglandin F2α receptor on hair follicle dermal papilla cells, influencing the hair growth cycle as follows:^1-5

Prolongation of Anagen Phase (Growth Phase):

Increases the duration of anagen, resulting in longer and thicker hair shafts.

Stimulation of Melanogenesis:

May enhance pigmentation in vellus hairs, making them appear darker and more terminal-like.

Increased Follicular Density:

Some studies suggest latanoprost may increase the number of follicles actively producing hair, particularly in the eyelash and eyebrow regions, and potentially the scalp.

Adverse Reactions

Common^1-5

Local irritation (itching, burning, erythema)
Hyperpigmentation of skin (especially around eyelids or eyebrows)
Increased pigmentation of treated hair
Eyelid darkening (rare with scalp use)
Unwanted hair growth if medication spreads to unintended areas
Eye irritation (if it migrates to eye area)

Contraindications & Precautions

Contraindications:

Known hypersensitivity to latanoprost or prostaglandin analogs
Active ocular conditions if near eyes (without ophthalmologic approval)
History of herpetic keratitis (due to prostaglandin-induced reactivation risk)

Precautions:

Avoid application near the eyes unless specifically prescribed
Use gloves or applicator to prevent unintended hair growth on fingers/hands
Avoid contact with mucous membranes
Patients with a history of uveitis, macular edema, or intraocular surgery should be monitored if periorbital application is required

Storage

Store refrigerated (2°C–8°C or 36°F–46°F);
Protect from light and heat

References

Johnstone, M. A. (1997). Hypertrichosis and increased pigmentation of eyelashes and adjacent hair in latanoprost therapy. American Journal of Ophthalmology, 120(7), 999–1001.
Blume-Peytavi, U., et al. (2012). Latanoprost stimulates human scalp hair growth in vivo. Journal of the American Academy of Dermatology, 66(5), 807–814.
Kwon, O. S., et al. (2007). Prostaglandin analogs as a potential treatment for hair loss: Latanoprost and bimatoprost in the management of alopecia. International Journal of Dermatology, 46(9), 1044–1048.
Clinical Pharmacology. Elsevier. Latanoprost Monograph. Accessed 2025
FDA Drug Label: Xalatan (latanoprost ophthalmic solution) https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=a98595b3-9f47- 48e0-b18d-550a2095f264&type=display Revised May 2023. Accessed June 15, 2025

Disclaimer

This sheet is a summary. It may not cover all possible drug information about this product. Call your doctor for medical advice and/or about side effects. You may report side effects to the FDA at 1-800-FDA-1088. A Wells Pharmacy Network pharmacist will be happy to answer any questions. For consultation, please call 1-800-622-4510.