Available Dosage Strengths
30%
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\Peels, in dermatology, refer to a method to exfoliate the epidermal layer. Glycolic acid (GA), an alpha-hydroxy acid, obtained from sugarcane, is the most common alpha-hydroxy acid peel. GA peels can be made in different pHs and concentrations depending on the depth of exfoliation that is needed. GA peels are made as free acids (low pH), partially neutralized (higher pH), buffered or esterified solutions in concentrations from 20% to 70%. Peels are used to treat acne vulgaris, melasma, wrinkles, actinic keratosis, photodamage, photoaging, pigmentation disorders, and acne scars.1,2
Therapeutically, GA peels can have anti-inflammatory, keratolytic, and antioxidant effects depending on the indication for the treatment. Mechanistically, GA targets the corneosome by enhancing breakdown and decreasing cohesiveness, causing desquamation. Peel intensity is determined by four factors 1) the concentration of the acid, 2) the vehicle used to carry it, 3) the amount of acid applied, and 4) the technique used. To neutralize the acidification, water or basic solutions such as ammonium salts, sodium bicarbonate, or sodium hydroxide are used. In addition, to the keratolytic activity of GA, it can increase the production of collagen in the dermis (the deeper layer of the skin). This can add integrity to the skin. Lastly, GA can facilitate the development of lipids in the epidermis, such as ceramides and cholesterol, which has a vital role in upholding a healthy skin barrier. By fortifying the barrier function, GA helps to prevent transepidermal water loss. This maintains optimal hydration of the skin.1,2
Common 1,3
Contraindications: 3
Precautions:
Store at 20–25°C (68–77°F) in a cool, dry place [9]. Protect from light and moisture to maintain stability.
This information is for educational purposes only. This compounded product has not been reviewed, approved, or evaluated by the Food and Drug Administration for safety and effectiveness. This product is not intended to diagnose, treat, cure, or prevent any disease. No claims are made regarding treatment, cure, or prevention of any disease or condition.
This information may not cover all possible drug information about this product. Call your doctor for medical advice and/or about side effects. You may report side effects to the FDA at 1-800-FDA-1088. A Wells Pharmacy Network pharmacist will be happy to answer any questions. For consultation, please call 1-800-622-4510.
