Materials Included in Kit:
(1) Nicotinamide Riboside Chloride (Niagen® Plus) Powder for Injection (500 mg vial)
(1) Bacteriostatic Water for Injection (30 mL vial)
Mixing Syringe (comes in two pieces):
– (1) 10 mL Mixing Syringe (without needle)
– (1) 22-Gauge Sterile Needle (do not use to administer subcutaneous injection)
(10) 1 mL Syringes (for administration use)
(20) Alcohol Prep Pads
Note: Your kit includes a 2-piece mixing syringe (10mL syringe + 22-gauge needle) for reconstitution, plus 10 separate 1mL syringes for injections. This video shows the reconstitution process only—individual injection technique is not demonstrated.
Detailed Preparation Steps:
1. Thoroughly wash hands using soap and hot water. Dry hands completely.
2. Remove the plastic safety cap from one vial.
3. Using an alcohol prep pad, thoroughly wipe the rubber stopper.
4. Repeat steps 2-3 on the second vial.
5. Attach the 22-Gauge Sterile Needle to the 10mL Mixing Syringe to assemble the Mixing Syringe.
6. Using the Mixing Syringe, draw the volume of bacteriostatic water indicated in the Table in your written instructions, according to the concentration prescribed by your health care provider.
IMPORTANT: Do not reconstitute Niagen® Plus Sterile Powder with less than 5mL of bacteriostatic water.
7. Inject the prescribed volume of bacteriostatic water from the Mixing Syringe into the Nicotinamide Riboside Chloride (Niagen® Plus) Powder for Injection 500mg vial.
8. Remove the Mixing Syringe and gently swirl the vial until the powder dissolves completely.
IMPORTANT: Discard the Mixing Syringe needle in a Sharps Container. Review your state/city regulations on safe needle disposal or consult your prescriber.
9. Verify the solution is clear, colorless, and free of particulates before use.
10. Refrigerate the reconstituted solution and store refrigerated between injections.
11. Discard any remaining contents after the 28-day beyond-use date.
Frequently Asked Questions
In addition to other screening parameters, consideration should be given to patients with the following conditions:
• Liver disease
• Kidney disease
• Prior diagnoses, including any form of cancer
• An unusual or allergic reaction to NR, NAD+, or other forms of vitamin B3
• Pregnant or trying to get pregnant
• Breast-feeding
The use of Niagen® Plus in children has not been studied; therefore, its use in children is not recommended.
At this time, NIAGEN® Plus has not been shown to interact with any medications. However, if an adverse reaction is observed, it is important to obtain a list of all prescription and over the counter medications, herbs, non-prescription drugs, or dietary supplements currently in use by the patient.
Though the following have been observed in one or more individuals, each individual is unique and such experiences may or may not be experienced by the patient. The following side effects have been observed in participants who were prescribed NIAGEN® Plus:
• Pain or discomfort (including a change in temperature) at the site of the injection.
• Infection at the site of the injection.
• Tingling to the face, extremities, or throughout the body
• Mild gastrointestinal disturbance, including nausea
• Tension in the muscles of the face
• Headache
• Sinus pressure
• Discomfort localized in areas of the body where issues may have been previously observed
• Change in energy level
This list may not describe all possible side effects.
Side effects from NIAGEN® Plus usually will resolve on their own. However, please seek medical attention for side effects that persist or are bothersome.
To report side effects of any drug, contact FDA’s toll-free information line, 1-888-INFO-FDA (1-888-463-6332). Press 2 to report into MedWatch or to receive instructions.
Store unopened vial in powder form and reconstituted material for further use at refrigerated temperature (2°C – 8°C / 35°F – 46°F).
If any of the following occur during therapy, discontinue use of NIAGEN® Plus, symptomatically treat, or seek immediate medical attention.
• Fever exceeding 101°F within 72 hours of receiving the injection
• Abnormal heart arrhythmia (spelling was wrong)
• Persistent diarrhea or vomiting
• Fainting or dizziness
Disclaimer: These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Please consult your healthcare provider for information and prescription information.
Prescribe with confidence. Compounded with care.
Ask your physician about Wells Pharmacy Network today for all of your compounding needs. If we haven’t yet made their acquaintance, let us know and we’ll be happy to have one of our Customized Medication Specialists contact them to discuss how our commitment to superior science and service makes us a leading compounding pharmacy capable of preparing custom medications that meet their requirements.
Patients with questions about an order, prescription, or medication, please call (866) 506-2174 and ask to speak to a pharmacist.
